Maxim Afinogenov also scored for the Sabres, who rallied from a 1-0 deficit to win their fourth straight. Ryan Miller made 27 saves as Buffalo won its sixth straight home game, its longest streak since winning seven straight early into the 1999-2000 season.
Shawn Horcoff scored for Edmonton, which has lost two straight to start a critical seven-game road trip as it attempts to climb back into playoff contention. The defending Western Conference champion entered the night seven points out of the eighth and final playoff spot.
Briere scored on a 2-on-1 break and at the end of a long shift. Getting a pass from Jochen Hecht inside the Oilers zone, Briere patiently waited for defender Toby Petersen to slide past him. Then, stepping into the middle, Briere beat Dwayne Roloson with a shot over the right shoulder.