Patrick Eaves, Jason Spezza, Dany Heatley and Dean McAmmond scored for Ottawa, which completed a four-game sweep of the season series against Florida. The Senators have won five of their past six games.
Jozef Stumpel and Olli Jokinen scored for Florida.
Florida’s Ed Belfour gave up four goals on nine shots, including three goals on the first three shots of the second period. He was pulled for Craig Anderson at 12:01 of the second.
Anderson had 10 saves for Florida. It was his first extensive play for Florida since replacing the injured Alex Auld on Feb. 19. Anderson played less than one minute at Atlanta on March 6.