Chris Neil and Peter Schaefer, both on the power play, and Daniel Alfredsson also had goals as the Senators (9-11-1) scored three times in the opening 20 minutes and before a crowd of 18,094 at Scotiabank Place went on to record their third victory in four games.
Twelve different players registered a point for Ottawa, which has now put together a win streak for just the second time in the season. The Senators won three straight games from Oct. 21-26.
Meanwhile, it was the fourth loss in the past five outings for the Wild (12-7-1), which has only two wins in its past eight contests and three victories in 10.
Pascal Dupuis had a power-play goal, Brian Rolston scored on a penalty shot and Mikko Koivu added a shorthanded goal for Minnesota, which received 28 saves from Manny Fernandez.
Wild defenceman Petteri Nummelin left the game with an apparent upper-body injury after he took a hit from Neil late in the first period and didn’t return. His status was not immediately known.
The Senators were boosted by the return of star defenceman Wade Redden, who was back in the lineup after missing eight of their past 11 games while trying to recover from a strained groin.
Ottawa got off to a quick start and Fernandez was forced into action early on, stopping Dany Heatley on a breakaway in the game’s opening minutes – one of 17 shots by the Senators in the first period.
Meszaros snuck a shot from the point through traffic to make it 1-0 just past the five-minute mark and Kelly scored at 6:12 on another breakaway attempt to double the lead.
Neil lifted a backhander from in close during a power play later in the period and the Senators led 3-0 after the first.
It was the Wild’s turn to go on the attack in the second but, after Alfredsson had made it 4-0, Dupuis’ power-play marker was the only reward it had to show for a 17-7 advantage in shots during the period.
In the third, Mike Fisher was called for covering the puck in the crease during a scramble in front of the Senators’ net and Rolston beat Emery with a deke to cut the lead to 4-2.
Schaefer and Koivu traded late goals to round out the scoring.
Minnesota went 1-for-5 on the power play, while Ottawa finished 2-for-3.
Notes: Ottawa’s Jason Spezza appeared in his 200th NHL game. … With Minnesota tough guy Derek Boogaard out with a leg injury, the Senators scratched enforcer Brian McGrattan. … Ottawa plays its next four games on the road, starting Wednesday at Philadelphia. … Centre Todd White, an Ottawa native, returned for the first time since the Senators traded him to Minnesota during the 2005 NHL draft. … The Wild, in Montreal on Wednesday, returns home to play host to Phoenix on Friday.