More than 15,000 - a record for the annual event - streamed into Rexall Place to watch.
Bergeron blazed around the ice surface in 14.392 seconds. He also won the hardest shot competition with a 103.5 miles-an-hour rocket.
Sykora picked apart four bullseye targets with five shots.
Lupul demonstrated his goal-scoring prowess to be crowned King of the Shootout.
Proceeds will benefit Ronald McDonald Children's Charities, the NHLPA Goals and Dreams Fund, and the Edmonton Oilers Community Foundation.