Chris Drury and Paul Gaustad also scored for the Sabres, who snapped a season-high, three-game regulation losing streak by beating the Bruins for the sixth straight time at home.
Maxim Afinogenov posted three assists for Buffalo, which went 6-7-1 in January.
Glen Murray scored for the Bruins, who lost their seventh straight road game. Boston has been outscored 19-3 during a four-game losing streak overall.