He scored with 10:24 left in the third period against the Philadelphia Flyers.
The 36-year-old native of Livonia, Mich., beat Flyers goaltender Antero Niittymaki with a quick shot from in front of the net for his 15th goal of the season. That pulled Modano within two of Joe Mullen for the career lead among U.S.-born players.
Modano joined Brendan Shanahan, Jaromir Jagr, Joe Sakic, Peter Bondra, Mats Sundin, Teemu Selanne and Mark Recchi as active 500-goal scorers.